Sources & References

Fine. is a symptom tracking tool. The questions in this app draw on established clinical research and recognized symptom frameworks. Fine. is not a diagnostic tool and does not provide medical diagnoses. Always consult a qualified healthcare provider.

Perimenopause

Symptom selection follows the Stages of Reproductive Aging Workshop +10 (STRAW+10) framework, the international gold standard for staging the menopause transition.

• Harlow SD, Gass M, Hall JE, et al. Executive summary of the Stages of Reproductive Aging Workshop +10. Menopause. 2012;19(4):387–395. pmc.ncbi.nlm.nih.gov/articles/PMC3340903
• The Menopause Society (formerly NAMS). menopause.org
• International Menopause Society. imsociety.org
• Davis SR, et al. Prevalence and severity of symptoms across the menopause transition (AMY Study). 2025.

Anxiety

Anxiety questions are adapted from the Generalized Anxiety Disorder 7-item scale (GAD-7), a widely used clinical instrument.

• Spitzer RL, Kroenke K, Williams JBW, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–1097.
• Pfizer GAD-7 / PHQ Screeners. phqscreeners.com

Depression

Depression questions are adapted from the Patient Health Questionnaire-9 (PHQ-9), a widely used clinical instrument.

• Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–613.
• Pfizer PHQ Screeners. phqscreeners.com

ADHD

ADHD-related questions reflect DSM-5 diagnostic criteria for adult ADHD, with attention to how symptoms commonly present in women.

• American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR). 2022.
• Solden S. Female ADHD Test: Symptoms in Women and Girls. ADDitude. additudemag.com/self-test-adhd-symptoms-women-girls
• Attention Deficit Disorder Association (ADDA). ADHD Symptoms in Adults. add.org/adhd-symptoms
• Dodson W. Rejection Sensitive Dysphoria. ADDitude

PMDD

PMDD-related questions reflect DSM-5-TR diagnostic criteria and best-practice symptom tracking from international PMDD organizations.

• American Psychiatric Association. DSM-5-TR. 2022.
• International Association for Premenstrual Disorders (IAPMD). iapmd.org
• Eisenlohr-Moul TA, et al. Carolina Premenstrual Assessment Scoring System (C-PASS). Am J Psychiatry. 2017.
• ACOG. Management of Premenstrual Disorders. 2023.

Endometriosis

Endometriosis-related questions reflect ACOG's 2026 clinical practice guideline, which supports symptom-based clinical evaluation.

• American College of Obstetricians and Gynecologists. Diagnosis of Endometriosis: ACOG Clinical Practice Guideline. 2026. acog.org
• ACOG patient resource: acog.org/womens-health/faqs/endometriosis

PCOS

PCOS-related questions reflect the Rotterdam diagnostic criteria as endorsed by the 2023 International Evidence-Based Guideline.

• International PCOS Network. 2023 International Evidence-Based Guideline for the Assessment and Management of PCOS. Endorsed by ASRM, ESHRE, and Monash University.
• Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria. Hum Reprod. 2004;19(1):41–47.

Thyroid (Hypo- and Hyperthyroidism)

Thyroid-related questions reflect symptom information from the American Thyroid Association and AACE clinical resources.

• American Thyroid Association. Hypothyroidism patient information. thyroid.org/hypothyroidism
• American Association of Clinical Endocrinology. Patient Journey: Thyroid Disease. aace.com/patient-journey/thyroid

Sleep, Sensory, Executive Function & Cross-Cutting Symptoms

Many symptoms tracked in Fine. cross multiple conditions. These are informed by the sources above and by general clinical literature on perimenopause, ADHD, anxiety, and depression.

Last updated: April 2026. Fine. is not a substitute for medical advice, diagnosis, or treatment.